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Objectives: To evaluate outcomes in patients embarking upon active surveillance for Prostate cancer (Pca) following tumour characterisation by modified transperineal template guided saturation biopsy.Materials and Methods: Of 500 patients with initial negative conventional transrectal ultrasound guided prostate biopsy underwent .. Read More
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Insights for the Inhibition of Cancer Progression: Revisiting Ca2+ and Camp Signalling Pathways
This editorial article gives insights for the inhibition of cancer progression. The pharmacological modulation of Ca2+/cAMP signalling interaction is also cited... Read More
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Cytotoxic properties of leaf, stem, and root extractions of Amorpha fruticosa were measured on PC-12 adrenal neural cells. Plant parts were processed via Soxhlet extraction method using a methanol solvent. Sterilized extractions of each plant component were applied to 48-hour PC-12 cells in increasing concentrations of 0.25 mg/ .. Read More
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Colorectal Cancer Awareness and Attitude among Adult, Al-Dammam, Saudi Arabia
Background: The aim of this study was to determine the level of knowledge about colorectal cancer (CRC) in adult healthy individuals in Eastern Province of Saudi Arabia. The main point of the current study was the need to increase the level of awareness of CRC to establish a link between the public, health centers and educationa.. Read More
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Theoretical uncertainties regarding the dimensions of mutator mutations are reflected particularly in the parameter uncertainties of the oncogenic pathways that are heterogeneous in individual tumor cells. The key attribute of marked heterogeneity in genomic lesions attests for the essential evolution of the mutator phenotype pe.. Read More
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Cancers Cured by Bio Electrons Photons
The K-BTE medical laser device releases sheaves of “biological electricity” through elementary laser beams of bio electron's photons. These sheaves of bio electricity are able to successfully attack and eradicate most types of malignant cancer with metastases including, prostate, breast, lungs, pancreatic, liver, bra.. Read More
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Objective: Despite the fact that cervical cancer is a preventable disease, it remains the second most common cancer in Bangladeshi women. This study investigated the knowledge of the risk factors, symptoms, and detection and prevention methods of carcinoma cervix among the females of reproductive age group in two urban areas of .. Read More
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The Effect of the Posterior Loading on the Spine of a School Child
The objective of this work is to study the effect of the backpack on the components of the spine system of a child school, know the effect of an eccentric force on the intervertebral discs, the creating a 3D model of the spine of a child of 38 kg overall weight under the effect of three eccentric load (P2, P3, P4) plus P1 compre.. Read More
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Cancer Moonshot Summit - Statement
In the US alone 600,000 cancer patients die on yearly basis, which has increased by a rate of 20 percent in the last couple of years. ÃÂis essential evidence speaks to the fact that today's standard medical technology just isn't working. Vice President Biden creates this national mission to launch this pion.. Read More
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Background: Lifestyle factors and genetic information has been found to contribute to the occurrence of lung cancer. This study assessed receptivity to participating in lifestyle programs to reduce cancer risk among unaffected lung cancer family members. We also explored demographic, medical, and psychosocial correlates of willi.. Read More
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Cemento-Ossifying Fibroma- A Case Report
Background: Cemento-Ossifying Fibroma (COF) is considered by most as relatively rare, benign, non-odontogenic neoplasm of the jaw bones and other craniofacial bones characterized by replacement of normal bone by fibrous tissue and varying amounts of newly formed bone or cementum-like material, or both. It commonly affects, adult.. Read More
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Delivery and effective modulation of intrinsically operative c-Myc gene amplification is a referential series of system pathways that appear to condition minimal platform utilization of dimensions that characterizes the outcomes as hyper-proliferation and increased growth rate, on the one hand, and of enhanced apoptotic activity.. Read More
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Purpose: To study the differences of ALDH1 expression in Invasive Ductal Carcinoma (IDC), Atypical Ductal Hyperplasia (ADH), Usual Ductal Hyperplasia (UDH) and normal ducts and their clinical significance.Materials and Methods: Immunohistochemistry method was used to detect the expression of ALDH1 in 160 cases of IDC, 50 cases o.. Read More
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Background: Laryngeal cancer is the most common malignancies of head neck region. The search for optimal treatment option for locally advanced laryngeal cancer is on throughout the world. Methodology: This was a prospective quasi experimental study carried out in the department of Radiation Oncology of NICRH, Dhaka and Square H.. Read More
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An Overview of Genetic Polymorphism and Lung Cancer Risk
The incidence and mortality rates of lung cancer in Asia have increased over the past few decades. Owing to the development of molecular-targeted drugs, the prognosis for patients with advanced stage lung cancer has improved. Despite this improvement the 5-year survival rate is very low. Accordingly, it is necessary to identify .. Read More
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Trailing the Path to Preventive Oncology
Cancer is one of the communicable diseases killing the mankind and is likely to be a global pandemic by year 2050. Fifty percent of cancers are preventable because of the causal association with modifiable risk factors. Preventive oncology is any measure that is taken to prevent development or progression of malignant process. A.. Read More
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Development of Microcantilever Sensors for Liver Cancer Detection
Recently, microcantilever-based technologies are playing more and more important roles in early diagnosis of cancer due to their high sensitivity, fast response, low cost, small reagent consumption, portability, real-time, labelfree detection, and so on. However, in conventional cantilever sensors working on mass-loading princip.. Read More
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Multiple Dimensions of Integrative De-Control in Permissiveness for Carcinogenesis
The overall profiles of malignant transformation events are multi-characterization of integral formulas of DNA damage that respond in highly varied manner as dictated by specific genotype dimensions. It is significant to view the overlapping of individual molecular pathways that progress as permissive players in the profile dime.. Read More
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Uterine Pathology in Hysterectomies Performed for Treatment of Pelvic Organ Prolapse
Objective: To determine the rate of uterine pathology in hysterectomies performed during surgery for treatment of uterovaginal prolapse. Methods: In this retrospective cohort study, we evaluated all patients undergoing hysterectomy during treatment of uterovaginal prolapse at a single academic institution from 2008 to 2013. Demo.. Read More
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