The maghemite magnetic nanoparticles may also be encapsulated with a fluorescent dye. These engineered fluorescent magnetic dualmodal nanoparticles have a great advantage due to the combination of the magnetic and fluorescence imaging into one nanostructured material. These nanoparticles, which also selectively marks Aβ40and insulin amyloid fibrils, might enable the early detection of plaques using both MRI and fluorescence microscopy, and therefore, may be applied in in vivo AD diagnosis studies.
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Last date updated on April, 2024