RNA has recently emerged as an important nanotechnology platform due to its extraordinary diversity in structure and function. Small interfering RNA (siRNA), showed significant potential in new molecular approaches to down-regulate specific gene expression in mammalian cells. In fact, targeted gene suppression by antisense DNA and siRNA has shown promising preclinical results, and/or is currently in clinical trials for a variety of diseases, including many forms of cancer (e.g., melanoma, neuroblastoma, and pancreatic adenocarcinoma), genetic disorders, and macular generation . Despite the high therapeutic potential of siRNA, its application for clinical medicine is still limited mainly due to the lack of appropriate delivery systems. In such a situation, the development of clinically suitable, safe, and effective drug-delivery biomaterials are required for the widespread use of siRNA therapeutics for disease treatment. Gene Silencing by siRNA Nanoparticles Synthesized via Sonochemical Method: Shimanovich U, Munder A, Loureiro A, Azoia NG, Gomes A, Cavaco-Paulo A, Gedanken A and Gruzman A. OMICS group encourages innovation in research field/scientific community. OMICS group encourages innovation in research field/scientific community. The published articles in OMICS journals include most of the trending topics. Molecular Biology has a very vast scope and covers all aspects in molecular sciences. Molecular biology journal publishes current research topics
Last date updated on April, 2024