Case 1 Case 2 Case 3 Case 4 Case 5 Case 6 Case 7 Case 8
Age 34 18 30 61 54 58 56 55
Gender female female female female female male female female
Duration of disease 11years and 3 months 4 months 8 years 5 years 14 months 15 years 23 years 10 years
Clinical feature1) Mild fever, decreased pulsation of left radial artery Fever of >38°C, bruits at neck and abdomen, abdominal pain, diarhea Decreased pulsation of left radial artery General fatigue, shoulder myalgia, decreased pulsation of left radial artery, bruis at neck Myalgia, arthralgia, general fatigue Fever>38°C, polyalthralgia, decreased pulsation of left radial artery, bruits at neck and abdomen Fever>38°C, polyalthralgia, decreased pulsation of left radial artery, Raynaud syndrome Consciousness loss, headache, myalgia, arthrlargia, erythema nodosum, bruit at both neck, blurred vision at left eye
Classification of angiography V I I V V V II
Coronary and/or pulmonary involvement C-, P- C-, P- C-, P- C:not done, P+ C-, P- C-, P- C-, P- C+, P-
Associated diseases Atopic dermatitis, ovarian cyst Aortic valve
regargitation
Compression fractures of vertebrae,depression None Gypertrophic myocarditis,Dementia Uveitis Mixed conective tissue disease, interstitial pneumonia, conprssion fracture of vertebrae, pneumocystis pneumonia Myoma uteri, ovarian cyst
Disease activity Moderately active Active phase Inactive phase Inactive phase Inactive phase Inactive phase Inactive phase Flared
Laboratory data2) 06/21/02 06/08/02 08/22/02 12/13/02 03/13/03 01/07/05 01/07/05 03/01/05
WBC (/mm3) 8,200 8,900 4,800 4,500 6,300 9,200 14,800 10,300
CRP (mg/dl) 4.1 7.7 0.1 0.2 0.1 0.3 5.1 2.4
ESR (/mm/hour) 36 111 11 13 11 8 17 43
Hb (g/dl) 10.6 9.8 11.7 13.7 12 14.5 7.7 10.2
Treatment3) PSL 5mg/d, etidronate disodium 200mg/d PSL40mg/d PSL 12mg/d, azatioprine 50mg/d, etidronate disodium 200mg/d Aspirin 100mg/d Aspirin 100mg/d, dipyridamole 200mg/d PSL5mg/d aspirin 100mg/d, PSL 5mg/d, antibiotics (micafungin,peatamidine,erythromiycin,doripenen) PSL30mg/d, aspirin 100mg/d, warfarin3mg/d,pravastatin 5mg/d
HLA-typing A29,31,B51,B52,DR2 A2,A24,B35,B52,DR2,DR4 A24,B52,DR2 A11,A31(19),B67, B61(40), Cw7, Cw3 B52,DR2 B39,B52 N.E B52
1): All clinical manifestations occurred during the course of disease are described. 2):Data indicate when sample was obtained. 3): Described when sample was obtained.
4):NE: not examined, PSL: prednisolone
A11,A31,(19),B67,B61(40), Cw7,Cw3
Table 1: Profiles of TA patients used in this study.