|
Case 1 |
Case 2 |
Case 3 |
Case 4 |
Case 5 |
Case 6 |
Case 7 |
Case 8 |
Age |
34 |
18 |
30 |
61 |
54 |
58 |
56 |
55 |
Gender |
female |
female |
female |
female |
female |
male |
female |
female |
Duration of disease |
11years and 3 months |
4 months |
8 years |
5 years |
14 months |
15 years |
23 years |
10 years |
Clinical feature1) |
Mild fever, decreased pulsation of left radial artery |
Fever of >38°C, bruits at neck and abdomen, abdominal pain, diarhea |
Decreased pulsation of left radial artery |
General fatigue, shoulder myalgia, decreased pulsation of left radial artery, bruis at neck |
Myalgia, arthralgia, general fatigue |
Fever>38°C, polyalthralgia, decreased pulsation of left radial artery, bruits at neck and abdomen |
Fever>38°C, polyalthralgia, decreased pulsation of left radial artery, Raynaud syndrome |
Consciousness loss, headache, myalgia, arthrlargia, erythema nodosum, bruit at both neck, blurred vision at left eye |
Classification of angiography |
I |
V |
I |
I |
V |
V |
V |
II |
Coronary and/or pulmonary involvement |
C-, P- |
C-, P- |
C-, P- |
C:not done, P+ |
C-, P- |
C-, P- |
C-, P- |
C+, P- |
Associated diseases |
Atopic dermatitis, ovarian cyst |
Aortic valve
regargitation |
Compression fractures of vertebrae,depression |
None |
Gypertrophic myocarditis,Dementia |
Uveitis |
Mixed conective tissue disease, interstitial pneumonia, conprssion fracture of vertebrae, pneumocystis pneumonia |
Myoma uteri, ovarian cyst |
Disease activity |
Moderately active |
Active phase |
Inactive phase |
Inactive phase |
Inactive phase |
Inactive phase |
Inactive phase |
Flared |
Laboratory data2) |
06/21/02 |
06/08/02 |
08/22/02 |
12/13/02 |
03/13/03 |
01/07/05 |
01/07/05 |
03/01/05 |
WBC (/mm3) |
8,200 |
8,900 |
4,800 |
4,500 |
6,300 |
9,200 |
14,800 |
10,300 |
CRP (mg/dl) |
4.1 |
7.7 |
0.1 |
0.2 |
0.1 |
0.3 |
5.1 |
2.4 |
ESR (/mm/hour) |
36 |
111 |
11 |
13 |
11 |
8 |
17 |
43 |
Hb (g/dl) |
10.6 |
9.8 |
11.7 |
13.7 |
12 |
14.5 |
7.7 |
10.2 |
Treatment3) |
PSL 5mg/d, etidronate disodium 200mg/d |
PSL40mg/d |
PSL 12mg/d, azatioprine 50mg/d, etidronate disodium 200mg/d |
Aspirin 100mg/d |
Aspirin 100mg/d, dipyridamole 200mg/d |
PSL5mg/d aspirin 100mg/d, |
PSL 5mg/d, antibiotics (micafungin,peatamidine,erythromiycin,doripenen) |
PSL30mg/d, aspirin 100mg/d, warfarin3mg/d,pravastatin 5mg/d |
HLA-typing |
A29,31,B51,B52,DR2 |
A2,A24,B35,B52,DR2,DR4 |
A24,B52,DR2 |
A11,A31(19),B67, B61(40), Cw7, Cw3 |
B52,DR2 |
B39,B52 |
N.E |
B52 |
1): All clinical manifestations occurred during the course of disease are described. 2):Data indicate when sample was obtained. 3): Described when sample was obtained.
4):NE: not examined, PSL: prednisolone
A11,A31,(19),B67,B61(40), Cw7,Cw3 |