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DataBiNS-Viz: A Web-Based Tool for Visualization of Non-Synonymous SNP Data

Fong Chun Chan1, Edward A. Kawas1, Mark D. Wilkinson1,2, Scott J. Tebbutt1,3*
1The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research
2Department of Medical Genetics
3Department of Medicine, Division of Respiratory Medicine; University of British Columbia, Providence
Heart + Lung Institute, St. Paul’s Hospital, Vancouver, BC, V6Z 1Y6, Canada
*Corresponding author: Dr. Scott J. Tebbutt, The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research,
Phone: 604-682-2344 ext. 63051,
Fax: 604-806-9274,
E-mail: stebbutt@mrl.ubc.ca
Received June 26, 2008; Accepted July 16, 2008; Published July 17, 2008
Citation: Fong CC, Edward AK, Mark DW, Scott JT (2008) DataBiNS-Viz: A Web-Based Tool for Visualization of Non- Synonymous SNP Data. J Proteomics Bioinform 1: 233-236. doi:10.4172/jpb.1000029
Copyright: © 2008 Fong CC, etal. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract

Here we describe DataBiNS-Viz – a visualization and exploration environment for non-synonymous coding single nucleotide polymorphisms (nsSNPs) data gathered by the BioMoby-based DataBiNS workflow. DataBiNSViz enables execution of the DataBiNS workflow on proteins described by KEGG, PubMed, or OMIM identifiers, followed by manual exploration of the integrated structure/function and pathway data for those proteins, with a particular focus on nsSNP data in-context. The tool can be freely accessed at http://bioinfo.icapture.ubc.ca:8090/DataBiNS (please use the Firefox or Safari web browsers). Examples of the retrieved data are given under the “Help on inputs” option. Detailed documentation can be accessed at: http://bioinfo.icapture.ubc.ca/mywiki/DataBiNS.

 
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