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VMD: Viral Microsatellite Database-A Comprehensive Resource for all Viral Microsatellites

Suresh B. Mudunuri1*, Allam Appa Rao2, S Pallamsetty3, Priyatosh Mishra1 and H.A.Nagarajaram4
1Department of Computer Science and Engineering, Aditya Engineering College, Surampalem, E.G.Dist, Andhra Pradesh -533437, India
2Vice-Chancellor, Jawaharlal Nehru Technological University, Kakinada, E.G.Dist, Andhra Pradesh - 533003, India
3Department of Computer Science and Systems Engineering, Andhra University College of Engineering (AUCE), Visakhapatnam, Andhra Pradesh - 530003, India
4Laboratory of Computational Biology, Centre for DNA Fingerprinting and Diagnostics (CDFD), Nampally, Hyderabad, Andhra Pradesh – 500001, India
*Corresponding author: Dr. Suresh B. Mudunuri,
Department of Computer Science and Engineering,
Aditya Engineering College, Surampalem,
E.G.Dist, Andhra Pradesh -533437, India,
Tel        : 55-16-36024532 / 36024538,
E-mail  : sureshverma@gmail.com
Received December 05, 2009; Accepted December 19, 2009; Published December 21, 2009
Citation: Mudunuri SB, Rao AA, Pal lamsetty S, Mishra P and Nagarajaram HA (2009) VMD: Viral Microsatellite Database-A Comprehensive Resource for all Viral Microsatellites. J Comput Sci Syst Biol 2: 283-286. doi:10.4172/jcsb.1000043
Copyright: © 2009 Mudunuri SB. This is an open-access article distributed under the terms of the Creative Commons Attribution License,which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Microsatellites are the small DNA sequences with a tandem repetition of a particular motif of size 1-6. Microsatellites are found in all known genomes and play a significant role in many fields including DNA Fingerprinting, Population Studies, Forensics, Paternity Studies, Gene Regulation, Genetic Disorder Studies, and Evolution of Genomes. They are extensively used as genetic markers for identifying pathogenic bacteria and viruses. More over, they are found to be associated with the plasticity, adaptation and virulence of bacteria and viruses. Insilico analysis of microsatellites in various viruses would reveal many interesting facts about their evolution and adaptation. To the best of our knowledge, there is no comprehensive and exclusive database of all viral microsatellites that extracts all types of microsatellites with flexible extraction options. In this paper, we describe the details of a relational database named Viral Microsatellite Database (VMD). VMD currently hosts microsatellites of around 3500 viral genomes along with their alignments, locus information, imperfection info, protein info etc. The database can be accessed and downloaded for free for academic / research purposes from http://www.mcr.org.in/vmd.
 
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